CHROMATOGRAPHY, Vol. 33 (2012), No. 3, pp. 145-155
Review
ISO 11843 Part7：ビジネス戦略としての検出限界推定法
ISO 11843 Part 7: Method for Estimating Detection Limit as Business Strategy
小谷明1、楠文代1、林 譲2
Akira Kotani1, Fumiyo Kusu1, Yuzuru Hayashi2
1Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392
2Teikyo Heisei University, 4-1 Uruidominami, Ichihara, Chiba 290-0193
Abstract:
ISO International Standards are strategic tools for business that reduce costs by minimizing waste and errors and increasing productivity. This paper takes ISO 11843 Part 7: Methodology based on stochastic properties of instrumental noise. This standard provides a method to estimate the detection limit from the noise and signal data involved in a chromatogram with no recourse to repeated measurements of real samples. Determination of epichatechin in HPLC with electrochemical detection is taken as an example. ISO 11843 Part 7 will help to improve global environments by saving time, energy, material and human efforts that would be required by repetition.
Keywords:
Detection limit, FUMI theory, ISO11843-7, Precision
