CHROMATOGRAPHY, Vol. 32 (2011), No. 3, pp. 141-152
Technical Review
蒸発光散乱検出器の有効的な使い方
How to Use Evaporative Light Scattering Detector Effectively
寺田英敏、早川禎宏、三上博久
Hidetoshi Terada, Yoshihiro Hayakawa and Hirohisa Mikami
Analytical and Measuring Instruments Division, Shimadzu Corporation
1 Nishinokyo-Kuwabaracho, Nakagyo-ku, Kyoto 604-8511, Japan
Abstract:
HPLC detectors are selected based on the specific properties of target compounds such as UV absorption, fluorescence and redox ability. However, some compounds have no such specific properties and a refractive index detector has been commonly used in those cases. In recent years, evaporative light scattering detector (ELSD) has been utilized for those compounds due to its wide range of applicability except for volatile compounds. In this paper, we review the principle, feature and know-how of ELSD and also introduce some applications by ELSD.
Keywords:
HPLC, evaporative light scattering detector, ELSD