CHROMATOGRAPHY, Vol. 24 (2003), No. 1, pp. 7-18
Miniaturization of Separation Systems and Its Applications
School of Materials Science, Toyohashi University of Technology
Toyohashi 441-8580, Japan.
Development of miniaturized separation system consisted of microscale extraction and liquid phase separation processes has been reviewed.
Various types of novel bonded stationary phases have been developed on the basis of the systematic analysis for the retention behavior of
polycyclic aromatic hydrocarbons on experimentally synthesized phases. In this review, the miniaturization of microscale sample preparation
technique and the effective on.line coupling to microcolumn liquid phase separations are also described especially focusing on the approach
by the author’s group. The novel use of synthetic polymer filaments as the stationary phase and extraction media in those microscale separation
systems will be introduced along with the applications in gas chromatographic separation.
miniaturization; sample preparation; microcolumn; on.line coupling; fibrous materials; liquid chromatography; gas chromatography