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Focussing Review
Genomics for Drug Discovery
Focusing on Proteome and Medicinal Genetics |
| Yoshiya Oda and Takeshi Nagasu |
Eisai Co., Ltd., Lab. of Seeds Finding Technology
Tokodai 5-1-3, Tsukuba, Ibaraki 300-2635, Japan |
Abstract:
Genomics will lead us to a new era of drug discovery, in which the final goal will be an individualized medicine. However the goal is still far and will be difficult to realize. In short, we must learn to utilize well and develop new techniques in genomics. In this document, we introduce the way of utilizing this technology, especially focusing on the proteome, and our new concept of "medicinal genetics". The quantitative proteome technology that we have developed will be a powerful tool for drug discovery and evaluation of proteins, direct target for drugs. In addition, medicinal genetics will serve as a short for genes to become drug targets, including target finding and validation.
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| Keywords: | proteome, genomics, genetics, drug discovery, bioinformatics, chemical genetics, target validation |
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