CHROMATOGRAPHY, Vol. 25 (2004), No. 1, pp. 25-32
Simultaneous Detection of Endocrine Disruptors of 4-Nonyl Phenols and
4-Octyl Phenols in Commodity Products Using Positive Chemical
Ionization-Gas Chromatography/Mass Spectrometry
*Yokohama City Institute of Health, 1-2-17 Takigashira, Isogo-ku, Yokohama, 234.0011, Japan
**Tokyo Metropolitan Research Laboratory of Public Health, 3-24-1 Hyakunincho, Shinjuku.ku, Tokyo, 169-0073, Japan
***PerkinElmer Japan, 2-8-4 Kitasaiwai, Nishi.ku, Yokohama, 220-0004, Japan
****Department of Materials Technology, Faculty of Engineering, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba, 263-8522, Japan
Alkyl phenol is the general name for phenol compounds with different length or branched alkyl groups. Among the alkyl phenol group, a series
of chemicals called nonyl phenols and octyl phenols that have C 9 or C 8 alkyl chains at the para position relative to the phenolic hydroxyl
group are used for additives of synthetic resin products and raw materials for non.ionic surfactants, are classified as the endocrine disruptors.
In this study a rapid, highly selective and sensitive analytical method using positive chemical ionization (PCI).GC/MS has been established
to determine trimethylsilyl derivatives of nonyl phenols and octyl phenols. Using this method, 18 isomers of 4.nonyl phenol and 8
isomers of 4.octyl phenol were separated and confirmed for the commercial resin products.
endocrine disruptor; nonyl phenols; octyl phenols; positive chemical ionization; GC/MS; commodity products